Background：This gene encodes a transcription factor that contains both basic helix-loop-helix and leucine zipper structural features. It regulates the differentiation and development of melanocytes retinal pigment epithelium and is also responsible for pigment cell-specific transcription of the melanogenesis enzyme genes. Heterozygous mutations in the this gene cause auditory-pigmentary syndromes, such as Waardenburg syndrome type 2 and Tietz syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified.
仕様
Synonyms：BHLHE32,bHLHe32,Class E basic helix-loop-helix protein 32,CMM8,Homolog of mouse microphthalmia,Mi,Microphthalmia associated transcription factor,Microphthalmia,mouse,homolog of,Microphthalmia-associated transcription factor,MITF,MITF,mitfa,nacre,WS2,WS2A,z3A.1
Host：Rabbit
Reactivity：Human,Mouse
Applications：WB
Concentration：1mg/ml
Immunogen：Recombinant protein of human MITF
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB1：500 - 1：2000
Gene_ID（human）：4286
Swissprot：O75030
Isotype：IgG
Research Areas：Cancer, Epigenetics and Nuclear Signaling, Immunology
