Background：This gene encodes a component of SCF complexes, which are composed of this protein, cullin 1, a ring-box protein, and one member of the F-box family of proteins. This protein binds directly to the F-box motif found in F-box proteins. SCF complexes are involved in the regulated ubiquitination of specific protein substrates, which targets them for degradation by the proteosome. Specific F-box proteins recognize different target protein（s）, and many specific SCF substrates have been identified including regulators of cell cycle progression and development. Studies have also characterized the protein as an RNA polymerase II elongation factor. Alternative splicing of this gene results in two transcript variants. A related pseudogene has been identified on chromosome 7.
仕様
Synonyms：Cyclin A/CDK2 associated p19,Cyclin A/CDK2 associated protein p19,Cyclin-A/CDK2-associated protein p19,EMC19,MGC34403,OCP 2,OCP II,OCP II protein,OCP-2,OCP-II,OCP2,OCPII,Organ of Corti protein 2,Organ of Corti protein II,OTTHUMP00000159379,OTTHUMP00000159380,OTTHUMP00000228275,OTTHUMP00000228276,OTTHUMP00000228278,OTTHUMP00000228279,OTTHUMP00000228281,p19A,p19skp1,RNA polymerase II elongation factor like protein,RNA polymerase II elongation factor like protein OCP2,RNA polymerase II elongation factor-like protein,S phase kinase associated protein 1,S phase kinase associated protein 1A,S phase kinase associated protein 1A p19A,S-phase kinase-associated protein 1,SIII,Skp 1,SKP 1A,skp1,SKP1,SKP1A,TCEB1L,Transcription Elongation Factor B 1 like,Transcription elongation factor B,Transcription elongation factor B SIII polypeptide 1 like
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB
Concentration：1mg/ml
Immunogen：Recombinant protein of human SKP1
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
