Background：The product encoded by this gene is a member of a RNA-binding protein family and possesses nucleolytic activity against cytotoxic lymphocyte （CTL） target cells. It has been suggested that this protein may be involved in the induction of apoptosis as it preferentially recognizes poly（A） homopolymers and induces DNA fragmentation in CTL targets. The major granule-associated species is a 15-kDa protein that is thought to be derived from the carboxyl terminus of the 40-kDa product by proteolytic processing. Alternative splicing resulting in different isoforms of this gene product has been described in the literature.
仕様
Synonyms：Cytotoxic granule associated RNA binding protein 1,Cytotoxic granule associated RNA binding protein,mTIA-1,Nucleolysin TIA 1 isoform p40 ,Nucleolysin TIA-1 isoform p40,Nucleolysin TIA1 isoform p40,p40 TIA 1,p40-TIA-1 （containing p15-TIA-1）,p40-TIA-1,RNA binding protein TIA 1,RNA binding protein TIA1,RNA-binding protein TIA-1,T-cell-restricted intracellular antigen-1,TIA 1,TIA 1 cytotoxic granule associated RNA binding protein ,Tia,TIA-1,TIA1,TIA1 cytotoxic granule associated RNA binding protein,TIA1 cytotoxic granule associated RNA binding protein like 1,TIA1 protein,TIA1,TIAL1,TIAR,WDM
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB
Concentration：1mg/ml
Immunogen：Recombinant protein of human TIA1
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB 1：500 - 1：2000
Gene_ID（human）：7072
Swissprot：P31483
Isotype：IgG
Research Areas：Cancer, Cell Biology, Epigenetics and Nuclear Signaling, Immunology
