Background：This gene encodes a 140 kDa protein that is stored in the alpha-granules of platelets and Weibel-Palade bodies of endothelial cells. This protein redistributes to the plasma membrane during platelet activation and degranulation and mediates the interaction of activated endothelial cells or platelets with leukocytes. The membrane protein is a calcium-dependent receptor that binds to sialylated forms of Lewis blood group carbohydrate antigens on neutrophils and monocytes. Alternative splice variants may occur but are not well documented.
仕様
Synonyms：Antigen CD62,CD62,CD62 antigen-like family member P,CD62P,GMP 140,GMP-140,GMP140,GMRP,Granule membrane protein 140,Granulocyte membrane protein,GRMP,LECAM 3,LECAM3,Leukocyte endothelial cell adhesion molecule 3,Leukocyte-endothelial cell adhesion molecule 3,LYAM3,P Selectin,P-selectin,PADGEM,Platelet activation dependent granule-external membrane protein,Platelet alpha granule membrane protein,PSEL,Selectin P （granule membrane protein 140kDa,antigen CD62）,SELP
Host：Rabbit
Reactivity：Mouse,Rat
Applications：WB
Concentration：1mg/ml
Immunogen：Recombinant protein of human SELP
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Dilution：WB1：500 - 1：2000
Gene_ID（human）：6403
Swissprot：P16109
Isotype：IgG
Research Areas：Cancer, Cardiovascular, Immunology, Stem cells
