Background: This protein belongs to the lipocalin family and is the specific carrier for retinol (vitamin A alcohol) in the blood. It delivers retinol from the liver stores to the peripheral tissues. In plasma, the RBP-retinol complex interacts with transthyretin which prevents its loss by filtration through the kidney glomeruli. A deficiency of vitamin A blocks secretion of the binding protein posttranslationally and results in defective delivery and supply to the epidermal cells.
仕様
Synonyms:OTTHUMP00000020114,OTTHUMP00000020115,OTTHUMP00000020116,Plasma retinol binding protein 4,Plasma retinol-binding protein,Plasma retinol-binding protein(1-176),PRBP,PRO2222,RBP,RBP4,RDCCAS,RET4,Retinol binding protein 4,Retinol binding protein 4 interstitial,Retinol binding protein 4 plasma
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:WB,IHC
Concentration:1mg/ml
Immunogen:Recombinant protein of human RBP4
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Dilution:WB1:500 - 1:2000 IHC1:50 - 1:200
Gene_ID(human):5950
Swissprot:P02753
Isotype:IgG
Research Areas:Cancer, Cardiovascular, Metabolism, Signal transduction