Background：The protein encoded by this gene is one of the three catalytic subunits of protein phosphatase 1 （PP1）. PP1 is a serine/threonine specific protein phosphatase known to be involved in the regulation of a variety of cellular processes, such as cell division, glycogen metabolism, muscle contractility, protein synthesis, and HIV-1 viral transcription. Increased PP1 activity has been observed in the end stage of heart failure. Studies in both human and mice suggest that PP1 is an important regulator of cardiac function. Mouse studies also suggest that PP1 functions as a suppressor of learning and memory. Three alternatively spliced transcript variants encoding different isoforms have been found for this gene.
仕様
Synonyms：Alpha isoform serine threonine protein phosphatase PP1alpha 1 catalytic subunit,Catalytic subunit,EC 3.1.3.16,MGC15877,MGC1674,PP 1A,PP-1A,PP1A,PP1A,PP1alpha,PP2C ALPHA,PP2CA,Ppp1ca,Protein Phosphatase 2C Alpha Isoform,Serine threonine protein phosphatase PP1 alpha catalytic subunit,Serine threonine protein phosphatase PP1 alpha catalytic subunit protein phosphatase 1,Serine/threonine-protein phosphatase PP1-alpha catalytic subunit
Host：Rabbit
Reactivity：Human,Mouse
Applications：WB,IHC
Concentration：1mg/ml
Immunogen：Recombinant protein of human PPP1CA
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB1：500 - 1：2000 IHC1：50 - 1：200
Gene_ID（human）：5499
Swissprot：P62136
Isotype：IgG
Research Areas：Cancer, Metabolism, Signal transduction
