Background：This gene encodes a member of the immunoglobulin family of cell adhesion molecules that functions in the glomerular filtration barrier in the kidney. The gene is primarily expressed in renal tissues, and the protein is a type-1 transmembrane protein found at the slit diaphragm of glomerular podocytes. The slit diaphragm is thought to function as an ultrafilter to exclude albumin and other plasma macromolecules in the formation of urine. Mutations in this gene result in Finnish-type congenital nephrosis 1, characterized by severe proteinuria and loss of the slit diaphragm and foot processes.
仕様
Synonyms：CNF,Nephrin,Nephrosis 1 congenital Finnish type,Nephrosis 1,congenital,Finnish type （nephrin）,NPHN,NPHN,NPHS 1,Nphs1,Renal glomerulus specific cell adhesion receptor,Renal glomerulus-specific cell adhesion receptor
Host：Rabbit
Reactivity：Mouse,Rat
Applications：WB
Concentration：1mg/ml
Immunogen：A synthetic peptide of human NPHS1
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
