Background：This gene encodes a member of the NOD （nucleotide-binding oligomerization domain） family. This member is a cytosolic protein. It contains an N-terminal caspase recruitment domain （CARD）, a centrally located nucleotide-binding domain （NBD）, and 10 tandem leucine-rich repeats （LRRs） in its C terminus. The CARD is involved in apoptotic signaling, LRRs participate in protein-protein interactions, and mutations in the NBD may affect the process of oligomerization and subsequent function of the LRR domain. This protein is an intracellular pattern-recognition receptor （PRR） that initiates inflammation in response to a subset of bacteria through the detection of bacterial diaminopimelic acid. Multiple alternatively spliced transcript variants differring in the 5' UTR have been described, but the full-length nature of these variants has not been determined.
仕様
Synonyms：CARD 4,CARD4,Caspase recruitment domain 4,Caspase recruitment domain containing protein 4,Caspase recruitment domain family member 4,Caspase recruitment domain protein 4,Caspase recruitment domain-containing protein 4,CLR 7.1,CLR7.1,NLR family CARD domain containing 1,NLRC 1,NLRC1,NOD 1,Nod1,NOD1 protein,NOD1,Nucleotide binding oligomerization domain containing 1,Nucleotide binding oligomerization domain leucine rich repeat and CARD domain containing 1,Nucleotide-binding oligomerization domain-containing protein 1,Protein Nod1
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB
Concentration：1mg/ml
Immunogen：Recombinant protein of human NOD1
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
