Background:The protein encoded by this gene, together with spectrin and actin, constitute the red cell membrane cytoskeletal network. This complex plays a critical role in erythrocyte shape and deformability. Mutations in this gene are associated with type 1 elliptocytosis (EL1). Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
仕様
Synonyms:4.1R,41,Band 4.1,E41P,EL 1,EL1,EL1 gene,Elliptocytosis 1,Elliptocytosis 1 RH linked,EPB 4.1,EPB 41,EPB4.1,Epb41,Erythrocyte membrane protein band 4.1 (elliptocytosis 1 RH linked),Erythrocyte membrane protein band 4.1,Erythrocyte surface protein band 4.1,HE,P4.1,Protein 4.1,Protein 4.1,red blood cell type
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:WB,IHC
Concentration:1mg/ml
Immunogen:Recombinant protein of human EPB41
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Dilution:WB1:500 - 1:2000 IHC1:50 - 1:200
Gene_ID(human):2035
Swissprot:P11171
Isotype:IgG
Research Areas:Cardiovascular, Signal transduction