Background：The protein encoded by this gene is a member of the TNF-receptor superfamily, and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand （TNFSF10/TRAIL/APO-2L）, and transduces an apoptosis signal. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. Two transcript variants encoding different isoforms and one non-coding transcript have been found for this gene.
仕様
Synonyms：Fas like protein,Apoptosis inducing protein TRICK2A/2B,Apoptosis inducing receptor TRAIL R2,CD262,CD262 antigen,Cytotoxic TRAIL receptor 2,Death domain containing receptor for TRAIL/Apo 2L,Death receptor 5,DR5,KILLER,KILLER/DR5,OTTHUMP00000123492,OTTHUMP00000123493,p53 regulated DNA damage inducible cell death receptor（killer）,TNF related apoptosis inducing ligand receptor 2,TNF-related apoptosis-inducing ligand receptor 2,TNFRSF10B,TR10B,TRAIL R2,TRAIL receptor 2,TRAIL-R2,TRAILR2,TRICK2,TRICK2A,TRICK2B,TRICKB,Tumor necrosis factor receptor like protein ZTNFR9,Tumor necrosis factor receptor superfamily member 10B,Tumor necrosis factor receptor superfamily,member 10b,ZTNFR9
Host：Rabbit
Reactivity：Human
Applications：WB
Concentration：1mg/ml
Immunogen：Recombinant protein of human TNFRSF10B
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB1：500 - 1：2000
Gene_ID（human）：8795
Swissprot：O14763
Isotype：IgG
Research Areas：Cancer, Cell Biology, Cardiovascular, Signal transduction
