Background：The protein encoded by this gene belongs to the aldo/keto reductase （AKR） superfamily and AKR7 family, which are involved in the detoxification of aldehydes and ketones. The AKR7 family consists of 3 genes that are present in a cluster on the p arm of chromosome 1. This protein, thought to be localized in the golgi, catalyzes the NADPH-dependent reduction of succinic semialdehyde to the endogenous neuromodulator, gamma-hydroxybutyrate. It may also function as a detoxication enzyme in the reduction of aflatoxin B1 and 2-carboxybenzaldehyde. Alternative splicing results in multiple transcript variants.
仕様
Synonyms：AFAR,AFAR1,AFB1 aldehyde reductase 1,AFB1 AR1,AFB1-AR 1,AFB1AR1,Aflatoxin aldehyde reductase,Aflatoxin B1 aldehyde reductase member 2,Aflatoxin beta1 aldehyde reductase,Aiar,AKR7,Akr7a2,Aldo keto reductase family 7,Aldo keto reductase family 7 member A2 aflatoxin aldehyde reductase,Aldo keto reductase family 7 member A2,Aldo keto reductase family 7,member A2 （aflatoxin aldehyde reductase）,Aldoketoreductase 7,ARK72,SSA reductase,Succinic semialdehyde reductase
Host：Rabbit
Reactivity：Human,Mouse
Applications：WB,IHC,IF
Concentration：1mg/ml
Immunogen：Recombinant protein of human AKR7A2
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
