Background：The product of this gene is a mitogen induced GTPase activating protein （GAP）. It exhibits a specific GAP activity for Ras-related regulatory proteins Rap1 and Rap2, but not for Ran or other small GTPases. This protein may also hamper mitogen-induced cell cycle progression when abnormally or prematurely expressed. It is localized to the perinuclear region. Two alternatively spliced variants encoding the same isoform have been characterized to date.
仕様
Synonyms：GTPase activating protein Spa 1,GTPase-activating protein Spa-1,MGC102688,MGC17037,p130 SPA-1,p130 SPA1,Signal induced proliferation associated 1,Signal induced proliferation associated gene 1,Signal induced proliferation associated protein 1,Signal-induced proliferation-associated protein 1,SIPA 1,Sipa-1,Sipa1,SIPA1,Spa1
Host：Rabbit
Reactivity：Human,Mouse
Applications：WB
Concentration：1mg/ml
Immunogen：Recombinant protein of human SIPA1
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB1：500 - 1：2000
Gene_ID（human）：6494
Swissprot：Q96FS4
Isotype：IgG
Research Areas：Cancer, Cell Biology, Epigenetics and Nuclear Signaling, Developmental biology, Signal transduction, Stem cells
