Background：The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase （PDE） family, and PDE8 subfamily. This PDE hydrolyzes the second messenger, cAMP, which is a regulator and mediator of a number of cellular responses to extracellular signals. Thus, by regulating the cellular concentration of cAMP, this protein plays a key role in many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
仕様
Synonyms：5''-cyclic phosphodiesterase 8A,cAMP specific cyclic nucleotide phosphodiesterase 8A ,FLJ16150,High affinity cAMP specific and IBMX insensitive 3'5' cyclic phosphodiesterase 8A ,High affinity cAMP-specific and IBMX-insensitive 3'',HsT19550,PDE 8A,PDE8A,PDE8A,Phosphodiesterase 8A ,Phosphodiesterase8A,Weakly similar to 3'5' cyclic nucleotide phosphodiesterase
Host：Rabbit
Reactivity：Mouse,Rat
Applications：WB
Concentration：1mg/ml
Immunogen：Recombinant protein of human PDE8A
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
