Background:The protein encoded by this gene is an RNA-binding nuclear protein that is a tumor-rejection antigen. This antigen possesses tumor epitopes capable of inducing HLA-A24-restricted and tumor-specific cytotoxic T lymphocytes in cancer patients and may be useful for specific immunotherapy. This gene product is found to be an important cellular factor for HIV-1 gene expression and viral replication. It also associates transiently with U6 and U4/U6 snRNPs during the recycling phase of the spliceosome cycle. This encoded protein is thought to be involved in the regulation of mRNA splicing.
仕様
Synonyms:DSAP1,hSART 3,hSART-3,P100,P110,p110(nrb),RP11 13G14,SART 3,SART-3,SART3,SART3,Squamous cell carcinoma antigen recognized by T cells 3,Squamous cell carcinoma antigen recognized by T-cells 3,Tat interacting protein of 110 kDa,Tat-interacting protein of 110 kDa,Tip110
Host:Rabbit
Reactivity:Human
Applications:WB
Concentration:1mg/ml
Immunogen:Recombinant protein of human SART3
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Dilution:WB1:500 - 1:2000
Gene_ID(human):9733
Swissprot:Q15020
Isotype:IgG
Research Areas:Cancer, Epigenetics and Nuclear Signaling, Microbiology