Background:The protein encoded by this gene is part of a protein complex required for the retrotranslocation or dislocation of misfolded proteins from the endoplasmic reticulum lumen to the cytosol, where they are degraded by the proteasome in a ubiquitin-dependent manner. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
仕様
Synonyms:SEL1L ERAD E3 Ligase Adaptor Subunit,Suppressor Of Lin-12-Like Protein 1,Suppressor Of Lin 12 (Sel-1), C. Elegans, Homolog Of,Sel-1 Suppressor Of Lin-12-Like 1 (C. Elegans),Sel-1 Suppressor Of Lin-12-Like (C. Elegans),Sel-1 Suppressor Of Lin-12-Like 1,Protein Sel-1 Homolog 1.
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:WB
Concentration:1mg/ml
Immunogen:Recombinant protein of human SEL1L
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Dilution:WB1:500 - 1:2000
Gene_ID(human):6400
Swissprot:Q9UBV2
Isotype:IgG
Research Areas:Cancer, Immunology, Signal transduction