Background：The protein encoded by this gene is a small GTPase of the Rho-subfamily, which regulates signaling pathways that control diverse cellular functions including cell morphology, migration, endocytosis and cell cycle progression. This protein is highly similar to Saccharomyces cerevisiae Cdc 42, and is able to complement the yeast cdc42-1 mutant. The product of oncogene Dbl was reported to specifically catalyze the dissociation of GDP from this protein. This protein could regulate actin polymerization through its direct binding to Neural Wiskott-Aldrich syndrome protein （N-WASP）, which subsequently activates Arp2/3 complex. Alternative splicing of this gene results in multiple transcript variants. Pseudogenes of this gene have been identified on chromosomes 3, 4, 5, 7, 8 and 20.
仕様
Synonyms：CDC42,CDC42,CDC42Hs,Cell division control protein 42 homolog,Cell division cycle 42 （GTP binding protein 25kDa）,Cell division cycle 42,dJ224A6.1.1 （cell division cycle 42 （GTP-binding protein,25kD））,dJ224A6.1.2 （cell division cycle 42 （GTP-binding protein,25kD））,G25K,G25K GTP-binding protein,Growth regulating protein,GTP binding protein 25kDa,Small GTP binding protein CDC42,TKS
Host：Rabbit
Reactivity：Human,Mouse
Applications：WB,IHC
Concentration：1mg/ml
Immunogen：Recombinant protein of human CDC42
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB1：500 - 1：2000 IHC1：50 - 1：200
Gene_ID（human）：998
Swissprot：P60953
Isotype：IgG
Research Areas：Cancer, Cell Biology, Epigenetics and Nuclear Signaling, Signal transduction
