Background：This gene encodes a protein containing tetratricopeptide repeat and a U-box that functions as a ubiquitin ligase/cochaperone. The encoded protein binds to and ubiquitinates shock cognate 71 kDa protein （Hspa8） and DNA polymerase beta （Polb）, among other targets. Mutations in this gene cause spinocerebellar ataxia, autosomal recessive 16. Alternative splicing results in multiple transcript variants. There is a pseudogene for this gene on chromosome 2.
仕様
Synonyms：Antigen NY CO 7,Antigen NY-CO-7,C terminus of Hsp70-interacting protein,Carboxy terminus of Hsp70 interacting protein,Carboxy terminus of Hsp70-interacting protein,Carboxy terminus of Hsp70p interacting protein,CHIP,CHIP,CLL associated antigen KW 8,CLL-associated antigen KW-8,E3 ubiquitin protein ligase CHIP,E3 ubiquitin-protein ligase CHIP,Heat shock protein A binding protein 2 （c terminal）,HSPABP2,NY CO 7,PP1131,SDCCAG7,Serologically defined colon cancer antigen 7,STIP1 homology and U Box containing protein 1,STIP1 homology and U box containing protein 1 E3 ubiquitin protein ligase,STIP1 homology and U box-containing protein 1,STUB 1,STUB1,UBOX 1,UBOX1
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB
Concentration：1mg/ml
Immunogen：Recombinant protein of human STUB1
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB1：500 - 1：2000
Gene_ID（human）：10273
Swissprot：Q9UNE7
Isotype：IgG
Research Areas：Cancer, Epigenetics and Nuclear Signaling, Signal transduction
