Background：This gene encodes a member of the BTB/POZ protein family. BTB/POZ proteins are involved in several cellular processes including proliferation, apoptosis and transcription regulation. The encoded protein is a transcriptional repressor that plays a role in stem cell self-renewal and pluripotency maintenance. The encoded protein also suppresses transcription of the candidate tumor suppressor Gadd45GIP1, and expression of this gene may play a role in the progression of multiple types of cancer. A pseudogene of this gene is located on the short arm of chromosome 9.
仕様
Synonyms：BEND8,BTB Domain Containing 14B,BTB/POZ domain-containing protein 14B,btbd14b,FLJ37383,NAC-1,NAC1,Nacc1,NACC1,Nucleus accumbens-associated protein 1
Host：Rabbit
Reactivity：Human,Mouse
Applications：WB
Concentration：1mg/ml
Immunogen：Recombinant protein of human NACC1
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB1：500 - 1：2000
Gene_ID（human）：112939
Swissprot：Q96RE7
Isotype：IgG
Research Areas：Cancer, Epigenetics and Nuclear Signaling, Developmental biology, Stem cells
