Background：This gene encodes a long chain base subunit of serine palmitoyltransferase. Serine palmitoyltransferase, which consists of two different subunits, is the key enzyme in sphingolipid biosynthesis. It catalyzes the pyridoxal-5-prime-phosphate-dependent condensation of L-serine and palmitoyl-CoA to 3-oxosphinganine. Mutations in this gene were identified in patients with hereditary sensory neuropathy type I.
仕様
Synonyms：KIAA0526,LCB 2,LCB2,LCB2a,Long chain base biosynthesis protein 2,Long chain base biosynthesis protein 2a,Serine palmitoyl CoA transferase 2,Serine palmitoyltransferase 2,Serine palmitoyltransferase long chain base subunit 2,Serine palmitoyltransferase subunit II,Serine-palmitoyl-CoA transferase 2,SPT 2,SPT2,SPTC2,SPTLC 2,Sptlc2
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB
Concentration：1mg/ml
Immunogen：Recombinant protein of human SPTLC2
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB1：500 - 1：2000
Gene_ID（human）：9517
Swissprot：O15270
Isotype：IgG
Research Areas：Cancer, Cardiovascular, Metabolism, Signal transduction
