Background：This gene encodes a protein that may be involved in the degradation of G proteins via the ubiquitin-dependent proteasome pathway. The encoded protein binds to members of subfamily A of the regulator of the G-protein signaling （RGS） family through an N-terminal leucine-rich region. This protein also has a central RING finger-like domain and E3 ubiquitin ligase activity. This protein is highly conserved from flies to humans. Defects in this gene may cause the autosomal recessive, infantile malignant form of osteopetrosis.
仕様
Synonyms：Chloride channel 7 beta subunit,GAIP-interacting protein N terminus,GIPN,GL,Grey lethal osteopetrosis,HSPC019,OPTB5,Osteopetrosis-associated transmembrane protein 1,Ostm1,OSTM1,OTTHUMP00000016938,OTTHUMP00000196342
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB
Concentration：1mg/ml
Immunogen：Recombinant protein of human OSTM1
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB1：500 - 1：2000
Gene_ID（human）：28962
Swissprot：Q86WC4
Isotype：IgG
Research Areas：Cancer, Cell Biology, Developmental biology, Signal transduction
