Background：The protein encoded by this gene may play a role in DNA repair during replication of damaged DNA. This protein recruits valosin containing protein （p97） to stalled DNA replication forks where it may prevent excessive translesional DNA synthesis and limit the number of DNA-damage induced mutations. It may also be involved in replication-related G2/M-checkpoint regulation. Deficiency of a similar protein in mouse causes chromosomal instability and progeroid phenotypes. Mutations in this gene have been associated with Ruijs-Aalfs syndrome （RJALS）. Alternatively spliced transcript variants have been identified.
仕様
Synonyms：C1orf124,CA124,Chromosome 1 open reading frame 124 ,DDDL1880,dJ876B10.3,PRO4323,RP5-876B10.3,Spartan,SprT-like domain at the N terminus,SprT-like N-terminal domain,Zinc finger RAD18 domain-containing protein C1orf124
Host：Rabbit
Reactivity：Human
Applications：WB
Concentration：1mg/ml
Immunogen：Recombinant protein of human SPRTN
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
