Background:This gene encodes a member of the profilin family of small actin-binding proteins. The encoded protein plays an important role in actin dynamics by regulating actin polymerization in response to extracellular signals. Deletion of this gene is associated with Miller-Dieker syndrome, and the encoded protein may also play a role in Huntington disease. Multiple pseudogenes of this gene are located on chromosome 1.
仕様
Synonyms:Actin binding protein,ALS18,Epididymis tissue protein Li 184a,OTTHUMP00000125244,PFN 1,Pfn,PFN1,PROF1,Profilin I,Profilin-1,Profilin1,ProfilinI
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:WB
Concentration:1mg/ml
Immunogen:Recombinant protein of human PFN1
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Dilution:WB1:500 - 1:2000
Gene_ID(human):5216
Swissprot:P07737
Isotype:IgG
Research Areas:Cancer, Cell Biology, Neuroscience, Signal transduction, Tags & Cell Markers