Background：The product of this gene belongs to the SNF2/RAD54 helicase family. It represents the main component of the nucleosome remodeling and deacetylase complex and plays an important role in epigenetic transcriptional repression. Patients with dermatomyositis develop antibodies against this protein. Somatic mutations in this gene are associated with serous endometrial tumors. Alternative splicing results in multiple transcript variants encoding different isoforms.
仕様
Synonyms：ATP dependent helicase CHD4,ATP-dependent helicase CHD4,CHD 4,CHD-4,CHD4,CHD4,Chromodomain helicase DNA binding protein 4,Chromodomain-helicase-DNA-binding protein 4,Mi 2 autoantigen 218 kDa protein,Mi 2b,Mi-2 autoantigen 218 kDa protein,Mi2 beta,Mi2-beta
Host：Rabbit
Reactivity：Human
Applications：WB
Concentration：1mg/ml
Immunogen：Recombinant protein of human CHD4
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB1：500 - 1：2000
Gene_ID（human）：1108
Swissprot：Q14839
Isotype：IgG
Research Areas：Cancer, Epigenetics and Nuclear Signaling, Immunology
