Background：This gene encodes the large and catalytic subunit of ribonucleotide reductase, an enzyme essential for the conversion of ribonucleotides into deoxyribonucleotides. A pool of available deoxyribonucleotides is important for DNA replication during S phase of the cell cycle as well as multiple DNA repair processes. Alternative splicing results in multiple transcript variants.
仕様
Synonyms：R1,Ribonucleoside diphosphate reductase large subunit,Ribonucleoside diphosphate reductase M1 chain,Ribonucleoside diphosphate reductase subunit M1,Ribonucleoside reductase,large subunit,Ribonucleoside-diphosphate reductase large subunit,Ribonucleoside-diphosphate reductase subunit M1,Ribonucleotide reductase large chain,Ribonucleotide reductase large subunit,Ribonucleotide reductase M1,Ribonucleotide reductase M1 polypeptide,Ribonucleotide reductase R1 subunit,Ribonucleotide reductase,M1 subunit,RIR 1,RIR1,RIR1,RR 1,RR1,RRM 1,RRM1
Host：Rabbit
Reactivity：Human,Mouse
Applications：WB,IHC
Concentration：1mg/ml
Immunogen：Recombinant protein of human RRM1
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Dilution：WB1：500 - 1：2000 IHC1：50 - 1：200
Gene_ID（human）：6240
Swissprot：P23921
Isotype：IgG
Research Areas：Cancer, Epigenetics and Nuclear Signaling
