Background:The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein functions as a transcriptional modulator activated by transforming growth factor-beta and is thought to play a role in the regulation of carcinogenesis.
仕様
Synonyms:DKFZP586N0721,DKFZp686J10186,hMAD 3,hMAD-3,hSMAD3,HSPC193,HST17436,JV15 2,JV15-2,JV152,LDS1C,LDS3,MAD (mothers against decapentaplegic Drosophila) homolog 3,MAD homolog 3,Mad homolog JV15 2,Mad protein homolog,MAD,mothers against decapentaplegic homolog 3,Mad3,MADH 3,MADH3,MGC60396,Mothers against decapentaplegic homolog 3,Mothers against DPP homolog 3,SMA and MAD related protein 3,SMAD 3,SMAD,SMAD family member 3,SMAD,mothers against DPP homolog 3,Smad3,SMAD3
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:WB
Concentration:1mg/ml
Immunogen:A synthetic peptide of human SMAD3
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Dilution:WB1:500 - 1:2000
Gene_ID(human):4088
Swissprot:P84022
Isotype:IgG
Research Areas:Cancer, Epigenetics and Nuclear Signaling, Metabolism, Signal transduction, Stem cells