Background：The protein encoded by this gene is a death domain containing adaptor molecule that interacts with TNFRSF1A/TNFR1 and mediates programmed cell death signaling and NF-kappaB activation. This protein binds adaptor protein TRAF2, reduces the recruitment of inhibitor-of-apoptosis proteins （IAPs） by TRAF2, and thus suppresses TRAF2 mediated apoptosis. This protein can also interact with receptor TNFRSF6/FAS and adaptor protein FADD/MORT1, and is involved in the Fas-induced cell death pathway.
仕様
Synonyms：9130005N23Rik,AA930854,TNFR1 associated DEATH domain protein,TNFR1-associated DEATH domain protein,TNFRSF1A associated via death domain,TNFRSF1A-associated via death domain,tradd,TRADD,Tumor necrosis factor receptor type 1 associated DEATH domain protein,Tumor necrosis factor receptor type 1-associated DEATH domain protein
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB
Concentration：1mg/ml
Immunogen：Recombinant protein of mouse TRADD
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB 1：500 - 1：2000
Gene_ID（human）：71609
Swissprot：Q3U0V2
Isotype：IgG
Research Areas：Cancer, Cell Biology, Cardiovascular
