Background:This gene encodes the heavy subunit of ferritin, the major intracellular iron storage protein in prokaryotes and eukaryotes. It is composed of 24 subunits of the heavy and light ferritin chains. Variation in ferritin subunit composition may affect the rates of iron uptake and release in different tissues. A major function of ferritin is the storage of iron in a soluble and nontoxic state. Defects in ferritin proteins are associated with several neurodegenerative diseases. This gene has multiple pseudogenes. Several alternatively spliced transcript variants have been observed, but their biological validity has not been determined.
仕様
Synonyms:Apoferritin,Cell proliferation inducing gene 15 protein,Cell proliferation-inducing gene 15 protein,F HC,Ferritin H subunit,Ferritin heavy chain,Ferritin heavy polypeptide 1,FHC,FRIH,FRIH,FTH 1,FTH,FTH1,FTH1 protein,FTHL 6,FTHL6,Iron overload autosomal dominant,MGC104426,N-terminally processed,OK/SW-cl.84,PIG 15,PIG15,Placenta immunoregulatory factor,PLIF,Proliferation inducing gene 15 protein,Proliferation inducing protein 15
Host:Rabbit
Reactivity:Human,Mouse
Applications:WB
Concentration:1mg/ml
Immunogen:Recombinant protein of human FTH1
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Dilution:WB1:500 - 1:2000
Gene_ID(human):2495
Swissprot:P02794
Isotype:IgG
Research Areas:Cancer, Cardiovascular, Metabolism, Neuroscience, Signal transduction