Background：This gene encodes a downstream nuclear effector of the Hippo signaling pathway which is involved in development, growth, repair, and homeostasis. This gene is known to play a role in the development and progression of multiple cancers as a transcriptional regulator of this signaling pathway and may function as a potential target for cancer treatment. Alternative splicing results in multiple transcript variants encoding different isoforms.
仕様
Synonyms：65 kDa Yes associated protein,65 kDa Yes-associated protein,COB1,YAp 1,YAP 65,YAP,YAP1,YAP1,YAP2,YAP65,yes -associated protein delta,Yes associated protein 1 65kDa,Yes associated protein 1,Yes associated protein 2,yes associated protein beta,YKI,Yorkie homolog
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB,IHC
Concentration：1mg/ml
Immunogen：A synthetic peptide of human YAP1
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB1：500 - 1：2000 IHC1：50 - 1：200
Gene_ID（human）：10413
Swissprot：P46937
Isotype：IgG
Research Areas：Cancer, Epigenetics and Nuclear Signaling, Signal transduction
