Background：This gene encodes a racemase. The encoded enzyme interconverts pristanoyl-CoA and C27-bile acylCoAs between their （R）- and （S）-stereoisomers. The conversion to the （S）-stereoisomers is necessary for degradation of these substrates by peroxisomal beta-oxidation. Encoded proteins from this locus localize to both mitochondria and peroxisomes. Mutations in this gene may be associated with adult-onset sensorimotor neuropathy, pigmentary retinopathy, and adrenomyeloneuropathy due to defects in bile acid synthesis. Alternatively spliced transcript variants have been described. Read-through transcription also exists between this gene and the upstream neighboring C1QTNF3 （C1q and tumor necrosis factor related protein 3） gene.
仕様
Synonyms：2 methylacyl CoA racemase,2-methylacyl-CoA racemase,Alpha methylacyl CoA racemase,Alpha-methylacyl-CoA racemase,Amacr,AMACR,AMACRD,CBAS4,EC 5.1.99.4,Macr1,RACE,RM
Host：Rabbit
Reactivity：Human,Mouse
Applications：WB
Concentration：1mg/ml
Immunogen：Recombinant protein of human AMACR
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB1：500 - 1：2000
Gene_ID（human）：23600
Swissprot：Q9UHK6
Isotype：IgG
Research Areas：Cell Biology, Metabolism, Signal transduction
