Background:The protein encoded by this gene is the tropomyosin-binding subunit of the troponin complex, which is located on the thin filament of striated muscles and regulates muscle contraction in response to alterations in intracellular calcium ion concentration. Mutations in this gene have been associated with familial hypertrophic cardiomyopathy as well as with dilated cardiomyopathy. Transcripts for this gene undergo alternative splicing that results in many tissue-specific isoforms, however, the full-length nature of some of these variants has not yet been determined.
仕様
Synonyms:Cardiac muscle troponin T,Cardiomyopathy dilated 1D (autosomal dominant),Cardiomyopathy hypertrophic 2,CMD1D,CMH2,CMPD2,cTnT,LVNC6,MGC3889,OTTHUMP00000033864,OTTHUMP00000033865,OTTHUMP00000033866,OTTHUMP00000033867,OTTHUMP00000033870,OTTHUMP00000218095,RCM3,TNNT 2,TNNT2,TNNT2,TnTc,Troponin T cardiac muscle,Troponin T type 2 (cardiac),Troponin T type 2 cardiac,Troponin T,cardiac muscle,Troponin T2 cardiac
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:WB
Concentration:1mg/ml
Immunogen:Recombinant Protein of human TNNT2
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Dilution:WB1:500 - 1:2000
Gene_ID(human):7139
Swissprot:P45379
Isotype:IgG
Research Areas:Cancer, Cardiovascular, Signal transduction, Stem cells