Background：This locus is frequently mutated in hereditary nonpolyposis colon cancer （HNPCC）. When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences （RER+ phenotype） found in HNPCC. Two transcript variants encoding different isoforms have been found for this gene.
仕様
Synonyms：BAT26,COCA 1,COCA1,DNA mismatch repair protein Msh2,FCC 1,FCC1,hMSH2,HNPCC 1,HNPCC,HNPCC1,LCFS2,MSH 2,Msh2,MSH2,MutS homolog 2,MutS homolog 2 colon cancer nonpolyposis type 1,MutS protein homolog 2
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB,IP
Concentration：1mg/ml
Immunogen：Recombinant protein of human MSH2
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB1：500 - 1：2000 IP1：20 - 1：50
Gene_ID（human）：4436
Swissprot：P43246
Isotype：IgG
Research Areas：Cancer, Epigenetics and Nuclear Signaling
