Background：NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene, RELA. Four transcript variants encoding different isoforms have been found for this gene.
仕様
Synonyms：Avian reticuloendotheliosis viral （v rel） oncogene homolog A,MGC131774,NF kappa B p65delta3,NFKB3,Nuclear Factor NF Kappa B p65 Subunit,Nuclear factor NF-kappa-B p65 subunit,Nuclear factor of kappa light polypeptide gene enhancer in B cells 3,Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3,OTTHUMP00000233473,OTTHUMP00000233474,OTTHUMP00000233475,OTTHUMP00000233476,OTTHUMP00000233900,p65,p65 NF kappaB,p65 NFkB,relA,TF65,Transcription factor p65,v rel avian reticuloendotheliosis viral oncogene homolog A （nuclear factor of kappa light polypeptide gene enhancer in B cells 3 （p65））,V rel avian reticuloendotheliosis viral oncogene homolog A,v rel reticuloendotheliosis viral oncogene homolog A （avian）,V rel reticuloendotheliosis viral oncogene homolog A,nuclear factor of kappa light polypeptide gene enhancer in B cells 3,p65
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB
Concentration：1mg/ml
Immunogen：A synthetic peptide of human RELA
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB1：500 - 1：2000
Gene_ID（human）：5970
Swissprot：Q04206
Isotype：IgG
Research Areas：Cancer, Cell Biology, Cardiovascular, Epigenetics and Nuclear Signaling, Metabolism, Microbiology, Neuroscience, Signal transduction
