Background：This gene is a candidate tumor suppressor gene which encodes a nuclear RNA binding protein that is a component of the spliceosome A complex. The encoded protein plays a role in the induction of cell cycle arrest and apoptosis through pre-mRNA splicing of multiple target genes including the tumor suppressor protein p53. This gene is located within the tumor suppressor region 3p21.3, and may play a role in the inhibition of tumor transformation and progression of several malignancies including lung cancer.
仕様
Synonyms：FLJ39876,G15,H37,LUCA 15,LUCA15,Protein G15,Putative tumor suppressor LUCA15,RBM 5,Rbm5,RBM5,Renal carcinoma antigen NY REN 9,Renal carcinoma antigen NY-REN-9,RMB 5,RMB5,RNA binding motif protein 5,RNA binding protein 5,RNA-binding motif protein 5,RNA-binding protein 5,Tumor suppressor LUCA15
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB
Concentration：1mg/ml
Immunogen：Recombinant protein of human RBM5
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB1：500 - 1：2000
Gene_ID（human）：10181
Swissprot：P52756
Isotype：IgG
Research Areas：Cancer, Epigenetics and Nuclear Signaling
