Background：This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 100％ identical to the mouse ortholog. It interacts with CDC25 phosphatases, RAF1 and IRS1 proteins, suggesting its role in diverse biochemical activities related to signal transduction, such as cell division and regulation of insulin sensitivity. It has also been implicated in the pathogenesis of small cell lung cancer. Two transcript variants, one protein-coding and the other non-protein-coding, have been found for this gene.
仕様
Synonyms：14 3 3 E,14 3 3 epsilon,14 3 3E,14-3-3 protein epsilon,14-3-3E,1433E,Epididymis luminal protein 2,FLJ45465,FLJ53559,HEL2,KCIP 1,KCIP1,MDCR,MDS,Mitochondrial import stimulation factor L subunit,Protein kinase C inhibitor protein1,Tyrosine 3 monooxygenase/tryptophan 5 monooxygenase activation protein,epsilon,Tyrosine 3 monooxygenase/tryptophan 5 monooxygenase activation protein,epsilon polypeptide,Tyrosine 3/tryptophan 5 monooxygenase activation protein epsilon polypeptide,YWHAE
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB
Concentration：1mg/ml
Immunogen：Recombinant protein of human YWHAE
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Dilution：WB1：500 - 1：2000
Gene_ID（human）：7531
Swissprot：P62258
Isotype：IgG
Research Areas：Cancer, Neuroscience, Signal transduction, Stem cells
