Background：The protein encoded by this gene belongs to a family of proteins that modulate activation of G proteins, which transduce extracellular signals received by cell surface receptors into integrated cellular responses. The N-terminal half of this protein contains 10 copies of leu-gly-asn （LGN） repeat, and the C-terminal half contains 4 GoLoco motifs, which are involved in guanine nucleotide exchange. This protein may play a role in neuroblast division and in the development of normal hearing. Mutations in this gene are associated with autosomal recessive nonsyndromic deafness （DFNB82）. Alternative splicing results in multiple transcript variants.
仕様
Synonyms：DFNB82,G protein signaling modulator 2 （AGS3 like C. elegans）,G protein signaling modulator 2,G-protein-signaling modulator 2,Gpsm2,GPSM2,HGNC：29501,LGN,LGN protein,Mosaic protein LGN,Pins
Host：Rabbit
Reactivity：Human,Mouse
Applications：WB
Concentration：1mg/ml
Immunogen：Recombinant protein of human GPSM2
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB1：1000 - 1：2000
Gene_ID（human）：29899
Swissprot：P81274
Isotype：IgG
Research Areas：Cancer, Cell Biology, Signal transduction
