Background：The protein encoded by this gene mediates transcriptional control by interaction with the activation function 2 （AF2） region of several nuclear receptors, including the estrogen, retinoic acid, and vitamin D3 receptors. The protein localizes to nuclear bodies and is thought to associate with chromatin and heterochromatin-associated factors. The protein is a member of the tripartite motif （TRIM） family. The TRIM motif includes three zinc-binding domains - a RING, a B-box type 1 and a B-box type 2 - and a coiled-coil region. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene.
仕様
Synonyms：E3 ubiquitin protein ligase TRIM24,E3 ubiquitin-protein ligase Trim24,hTIF1,PTC6,RING finger protein 82,RNF82,TF1A,TIF1,TIF1-alpha,TIF1A,TIF1A,TIF1ALPHA,Transcription intermediary factor 1-alpha,Transcriptional intermediary factor 1 alpha,Transcriptional intermediary factor 1,Trim24,Tripartite motif containing 24,Tripartite motif-containing protein 24
Host：Rabbit
Reactivity：Human
Applications：WB
Concentration：1mg/ml
Immunogen：Recombinant protein of human TRIM24
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB1：1000 - 1：2000
Gene_ID（human）：8805
Swissprot：O15164
Isotype：IgG
Research Areas：Cancer, Epigenetics and Nuclear Signaling, Signal transduction
