Background：The protein encoded by this gene is a leucine-rich repeat-containing receptor （LGR） and member of the G protein-coupled, 7-transmembrane receptor （GPCR） superfamily. The encoded protein is a receptor for R-spondins and is involved in the canonical Wnt signaling pathway. This protein plays a role in the formation and maintenance of adult intestinal stem cells during postembryonic development. Several transcript variants encoding different isoforms have been found for this gene.
仕様
Synonyms：FEX,G protein coupled receptor 49,G protein coupled receptor 67,g protein-coupled receptor fex,G-protein coupled receptor 49,G-protein coupled receptor 67,G-protein coupled receptor HG38,GPR 49,GPR 67,GPR49,GPR67,GRP 49,GRP49,HG 38,HG38,Leucine rich repeat containing G protein coupled receptor 5,Leucine-rich repeat-containing G-protein coupled receptor 5,LGR 5,LGR5,LGR5,MGC117008,Orphan G protein coupled receptor HG38
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB
Concentration：1mg/ml
Immunogen：Recombinant protein of human LGR5
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Dilution：WB1：1000 - 1：2000
Gene_ID（human）：8549
Swissprot：O75473
Isotype：IgG
Research Areas：Cancer, Signal transduction, Stem cells
