Background：This gene encodes a voltage-dependent anion channel （VDAC）, and belongs to the mitochondrial porin family. VDACs are small, integral membrane proteins that traverse the outer mitochondrial membrane and conduct ATP and other small metabolites. They are known to bind several kinases of intermediary metabolism, thought to be involved in translocation of adenine nucleotides, and are hypothesized to form part of the mitochondrial permeability transition pore, which results in the release of cytochrome c at the onset of apoptotic cell death. Alternatively transcript variants encoding different isoforms have been described for this gene.
仕様
Synonyms：hVDAC3,mVDAC3,Outer mitochondrial membrane protein porin 3,voltage dependent anion channel 3
Host：Rabbit
Reactivity：Human
Applications：WB
Concentration：1mg/ml
Immunogen：Recombinant protein of human VDAC3
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB 1：1000 - 1：2000
Gene_ID（human）：7419
Swissprot：Q9Y277
Isotype：IgG
Research Areas：Cancer, Cell Biology, Metabolism, Signal transduction
