Background:The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. Studies in mouse suggest that this protein plays a role in DNA postreplication repair.
仕様
Synonyms:Bendless like ubiquitin conjugating enzyme,Bendless-like ubiquitin-conjugating enzyme,BLU,EC 6.3.2.19,Epididymis secretory protein Li 71,HEL-S-71,Human epidermoid carcinoma mRNA for ubiquitin-conjugating enzyme E2 similar to Drosophila bendless gene product complete cds,MGC131857,MGC8489,UBC 13,Ubc13,UbCH ben,UbcH-ben,UbcH13,UBCHBEN,Ube 2N,Ube2n,UBE2N,Ubiquitin carrier protein N,Ubiquitin conjugating enzyme E2 N,Ubiquitin conjugating enzyme E2N (homologous to yeast UBC13),Ubiquitin conjugating enzyme E2N (UBC13 homolog yeast),Ubiquitin conjugating enzyme E2N,Ubiquitin protein ligase N,Ubiquitin-conjugating enzyme E2 N,Ubiquitin-protein ligase N,Yeast UBC13 homolog
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:WB
Concentration:1mg/ml
Immunogen:Recombinant protein of human UBE2N
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Dilution:WB1:1000 - 1:2000
Gene_ID(human):7334
Swissprot:P61088
Isotype:IgG
Research Areas:Cancer, Cell Biology, Epigenetics and Nuclear Signaling, Immunology