Background：This gene encodes one of the two alpha chains of type XI collagen, a minor fibrillar collagen. It is located on chromosome 6 very close to but separate from the gene for retinoid X receptor beta. Type XI collagen is a heterotrimer but the third alpha chain is a post-translationally modified alpha 1 type II chain. Proteolytic processing of this type XI chain produces PARP, a proline/arginine-rich protein that is an amino terminal domain. Mutations in this gene are associated with type III Stickler syndrome, otospondylomegaepiphyseal dysplasia （OSMED syndrome）, Weissenbacher-Zweymuller syndrome, autosomal dominant non-syndromic sensorineural type 13 deafness （DFNA13）, and autosomal recessive non-syndromic sensorineural type 53 deafness （DFNB53）. Alternative splicing results in multiple transcript variants. A related pseudogene is located nearby on chromosome 6.
仕様
Synonyms：COBA2,COL11A2,Collagen alpha 2（XI）,Collagen alpha-2（XI） chain,Collagen type XI alpha 2,Collagen XI a2,DAQB-79P13.8,DFNA13,DFNB53,FBCG2,HGNC：2187,HKE5,PARP,Pro a2 chain of collagen type XI,STL3
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB
Concentration：1mg/ml
Immunogen：Recombinant protein of human COL11A2
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
