Background：This gene encodes the enzyme which is involved in the early steps of L-serine synthesis in animal cells. L-serine is required for D-serine and other amino acid synthesis. The enzyme requires NAD/NADH as a cofactor and forms homotetramers for activity. Mutations in this gene have been found in a family with congenital microcephaly, psychomotor retardation and other symptoms. Multiple alternatively spliced transcript variants have been found, however the full-length nature of most are not known.
仕様
Synonyms：3 PGDH,3-PGDH,3-phosphoglycerate dehydrogenase,3PGDH,D-3-phosphoglycerate dehydrogenase,EC 1.1.1.95,Epididymis secretory protein Li 113,HEL S 113,NLS,NLS1,PDG,PGAD,PGD,PGDH,PGDH3,Phgdh,PHGDHD,Phosphoglycerate dehydrogenase,SERA,SERA
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB,IHC
Concentration：1mg/ml
Immunogen：Recombinant protein of human PHGDH
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB1：500 - 1：2000 IHC1：50 - 1：200
Gene_ID（human）：26227
Swissprot：O43175
Isotype：IgG
Research Areas：Cancer, Metabolism, Neuroscience, Signal transduction
