Background:This gene belongs to the splicing factor SR family of genes. U2 auxiliary factor, comprising a large and a small subunit, is a non-snRNP protein required for the binding of U2 snRNP to the pre-mRNA branch site. This gene encodes the small subunit which plays a critical role in both constitutive and enhancer-dependent RNA splicing by directly mediating interactions between the large subunit and proteins bound to the enhancers. Alternatively spliced transcript variants encoding different isoforms have been identified.
仕様
Synonyms:DKFZp313J1712,FP793,Human U2 snRNP auxiliary factor small subunit9,RN,RNU2AF1,Splicing factor U2AF 35 kDa subunit,U2 auxiliary factor 35 kDa subunit,U2 small nuclear ribonucleoprotein auxillary factor 35 KD subunit,U2 small nuclear RNA auxiliary factor 1,U2 snRNP auxiliary factor small subunit,U2(RNU2) small nuclear RNA auxiliary factor 1,U2(RNU2) small nuclear RNA auxiliary factor binding protein,U2AF1,U2AF1,U2AF35,U2AFBP
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:WB,IHC
Concentration:1mg/ml
Immunogen:Recombinant protein of human U2AF1
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Dilution:WB1:500 - 1:2000 IHC1:50 - 1:200
Gene_ID(human):7307
Swissprot:Q01081
Isotype:IgG
Research Areas:Cancer, Epigenetics and Nuclear Signaling