Background：The protein encoded by this gene is a membrane mannose-specific lectin that cycles between the endoplasmic reticulum, endoplasmic reticulum-Golgi intermediate compartment, and cis-Golgi, functioning as a cargo receptor for glycoprotein transport. The protein has an N-terminal signal sequence, a calcium-dependent and pH-sensitive carbohydrate recognition domain, a stalk region that functions in oligomerization, a transmembrane domain, and a short cytoplasmic domain required for organelle targeting. Allelic variants of this gene are associated with the autosomal recessive disorder combined factor V-factor VIII deficiency.
仕様
Synonyms：Endoplasmic reticulum golgi intermediate compartment protein 53 ,ER-Golgi intermediate compartment 53 kDa protein,ERGIC-53,ERGIC53,ERGIC53 like protein,F5F8D,FMFD1,Gp58,Intracellular mannose specific lectin ,Intracellular mannose-specific lectin MR60,Lectin mannose binding 1 ,Lectin mannose-binding 1,Lman1,LMAN1 like protein ,LMAN1,MCFD1,MR60,Protein ERGIC-53
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB
Concentration：1mg/ml
Immunogen：Recombinant protein of human LMAN1
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
