Background:This gene encodes a member of the DEAD box protein family. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The protein encoded by this gene can shuttle between the nucleus and the cytoplasm, and has an RNA-independent ATPase activity. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
仕様
Synonyms:DDX47,DDX47,DEAD (Asp Glu Ala Asp) box polypeptide 47,DEAD box helicase 47,DEAD box protein 47,DKFZp564O176 ,E4 DBP,FLJ30012 ,HGNC:18682,HQ0256 ,MSTP162 ,Probable ATP dependent RNA helicase DDX47,Probable ATP-dependent RNA helicase DDX47
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:WB
Concentration:1mg/ml
Immunogen:Recombinant protein of human DDX47
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Dilution:WB 1:500 - 1:2000
Gene_ID(human):51202
Swissprot:Q9H0S4
Isotype:IgG
Research Areas:Cancer, Epigenetics and Nuclear Signaling