Background:The protein encoded by this gene plays a key role in the acute regulation of steroid hormone synthesis by enhancing the conversion of cholesterol into pregnenolone. This protein permits the cleavage of cholesterol into pregnenolone by mediating the transport of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane. Mutations in this gene are a cause of congenital lipoid adrenal hyperplasia (CLAH), also called lipoid CAH. A pseudogene of this gene is located on chromosome 13.
仕様
Synonyms:Cholesterol trafficker,Luteinizing hormone induced protein,mitochondrial,Mitochondrial steroid acute regulatory protein,StAR,StAR related lipid transfer (START) domain containing 1,STAR,StARD1,START domain containing 1,START domain containing protein 1,START domain-containing protein 1,Steroid acute regulatory protein,Steroidogenic acute regulator,Steroidogenic acute regulatory protein,Steroidogenic acute regulatory protein mitochondrial
Host:Rabbit
Reactivity:Human,Mouse
Applications:WB,IF
Concentration:1mg/ml
Immunogen:Recombinant protein of human STAR
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Dilution:WB1:500 - 1:2000 IF1:50 - 1:200
Gene_ID(human):6770
Swissprot:P49675
Isotype:IgG
Research Areas:Cancer, Metabolism, Signal transduction