Background：This gene encodes a protein involved in regulation of the cell cycle through interactions with several cyclin-dependent kinases. One study （PMID： 16177568） reported aberrant splicing of transcripts from this gene which results in removal of the cyclin binding domain only in human cancer cells, and reduction in gene expression was shown in colorectal cancers （PMID： 17982127）.Multiple transcript variants encoding different isoforms have been found for this gene.
仕様
Synonyms：CABL1,CABLES,Cables1,Cdk5 and Abl enzyme substrate 1,CDK5 and ABL1 enzyme substrate 1,FLJ35924,HsT2563,IK3 1,Ik3-1,Interactor with CDK3 1
Host：Rabbit
Reactivity：Human,Mouse
Applications：WB
Concentration：1mg/ml
Immunogen：Recombinant protein of human CABLES1
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
