Background：The product of this gene is a member of the OTU （ovarian tumor） superfamily of predicted cysteine proteases. The encoded protein is a highly specific ubiquitin iso-peptidase, and cleaves ubiquitin from branched poly-ubiquitin chains but not from ubiquitinated substrates. It interacts with another ubiquitin protease and an E3 ubiquitin ligase that inhibits cytokine gene transcription in the immune system. It is proposed to function in specific ubiquitin-dependent pathways, possibly by providing an editing function for polyubiquitin chain growth. Alternative splicing results in multiple transcript variants.
仕様
Synonyms：Deubiquitinating enzyme OTUB1,hOTU1,HSPC263,OTB1,OTU domain containing ubiquitin aldehyde binding protein 1,OTU domain,ubiquitin aldehyde binding 1,OTU domain-containing Ubal-binding protein 1,OTU domain-containing ubiquitin aldehyde-binding protein 1,OTU-domain Ubal-binding 1,OTU1,Otub1,OTUB1,Otubain 1,Otubain-1,Ubiquitin specific processing protease OTUB1,Ubiquitin thioesterase OTUB1,ubiquitin-specific protease otubain 1,Ubiquitin-specific-processing protease OTUB1
Host：Rabbit
Reactivity：Human,Mouse
Applications：WB
Concentration：1mg/ml
Immunogen：A synthetic peptide of human OTUB1
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB1：500 - 1：2000
Gene_ID（human）：55611
Swissprot：Q96FW1
Isotype：IgG
Research Areas：Cancer, Cell Biology, Epigenetics and Nuclear Signaling
