Background：This gene encodes a core component of the exosome. The mammalian exosome is required for rapid degradation of AU rich element-containing RNAs but not for poly（A） shortening. The association of this protein with the exosome is mediated by protein-protein interactions with ribosomal RNA-processing protein 42 and ribosomal RNA-processing protein 46. Alternative splicing of this gene results in multiple transcript variants.
仕様
Synonyms：3'-5' exoribonuclease CSL4 homolog,CGI 108,CGI-108,CSL4,CSL4 exosomal core protein homolog,CSL4, S. cerevisiae, homolog of,Csl4p,EXOS1,Exosc1,Exosomal core protein CSL4,Exosome complex component csl4,Exosome component 1,hCsl4p,Homolog of yeast exosomal core protein CSL4,p13,RP11-452K12.9,SKI4,Ski4p
Host：Rabbit
Reactivity：Human
Applications：WB
Concentration：1mg/ml
Immunogen：Recombinant protein of human EXOSC1
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB1：500 - 1：2000
Gene_ID（human）：51013
Swissprot：Q9Y3B2
Isotype：IgG
Research Areas：Cancer, Epigenetics and Nuclear Signaling
