Background：This gene encodes a protein containing multiple ankyrin domains and two IQ calmodulin-binding domains. The encoded protein may function in renal tubular development and function, and in left-right axis determination. This protein interacts with nephrocystin and infers a connection between primary cilia function and left-right axis determination. A similar protein in mice interacts with calmodulin. Mutations in this gene have been associated with nephronophthisis type 2. Multiple transcript variants encoding distinct isoforms have been identified for this gene.
仕様
Synonyms：INV ,Inversion of embryo turning homolog ,inversion of embryonic turning,INVS,Nephrocystin 2,Nephrocystin-2,Nephrocystin2,nephronophthisis 2 （infantile）,NPH2 ,NPHP2
Host：Rabbit
Reactivity：Human,Mouse
Applications：WB
Concentration：1mg/ml
Immunogen：Recombinant protein of human INVS
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB1：500 - 1：2000
Gene_ID（human）：27130
Swissprot：Q9Y283
Isotype：IgG
Research Areas：Cancer, Signal transduction, Stem cells
