Background：The protein encoded by this gene is a coiled-coil-forming protein that associates with the SNARE （soluble N-ethylmaleimide-sensitive fusion protein attachment protein receptor） complex of proteins and the BLOC-1 （biogenesis of lysosome-related organelles） complex. Biochemical studies have identified additional binding partners. As part of the SNARE complex, it is required for vesicle docking and fusion and regulates neurotransmitter release. The BLOC-1 complex is required for the biogenesis of specialized organelles such as melanosomes and platelet dense granules. Mutations in gene products that form the BLOC-1 complex have been identified in mouse strains that are models of Hermansky-Pudlak syndrome. Alternative splicing results in multiple transcript variants.
仕様
Synonyms：OTTHUMP00000035157,SNAP associated protein,SNAP-25-binding protein,SNAP-associated protein,SNAP25BP,SNAPAP,Snapin,SNAPN,SNARE associated protein snapin,SNARE-associated protein Snapin,Synaptosomal associated protein 25 binding protein,Synaptosomal-associated protein 25-binding protein
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB
Concentration：1mg/ml
Immunogen：Recombinant protein of human SNAPIN
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
